Depo-Provera injection contains the active ingredient medroxyprogesterone acetate, which is a synthetic form of the naturally occurring female sex hormone, progesterone. Depo-Provera injection is a long-term form of contraception. It is usually given into the muscle of the buttock or upper arm. The injection produces a reservoir of medroxyprogesterone in the muscle, which is then continuously released into the bloodstream over a period of 12 weeks.
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